时间：2016年10月6日（周四）上午10：00
地点：仓山校区光电与信息工程学院四层学术报告厅
主讲：加拿大多伦多大学，Lothar Lilge 教授
主办：光电与信息工程学院
报告摘要：Light based therapies for oncology and other medical indications gain increasing penetration in the medical sciences. However, one of the major limitations pertains to the ability to deliver a predetermined dose within the target tissue. Light-based therapies are commonly based on the delivered irradiance or radiance exposure for illumination through surfaces or Energy per tissue volume. However, due to neglecting the tissue geometry and the unknown tissue optical properties the actually delivered photon dose can vary significantly, limiting the response rates and ultimately patient and physician confidence. To improve the outcome of light based therapies we developed a process which utilizes clinical imaging data to obtain the patients anatomical details from which 3D tetrahedral models are created. The model is used in Monte Carlo simulation based on population average tissue optical properties to optimize the irradiance or radiant exposure to achieve the desired dose at depth. Examples of light propagation models for low level laser therapy, bladder irradiation and irradiation in bone metastasis are explained. The use of these simulations for PDT treatment planning is presented in an example, which include the workflow from medical images to photon density distribution.